King's Daughters Hospital is located on Grand Avenue. From US Highway 49 turn west onto East 15th Street. Turn left on Grand Avenue. KDH is in the 7th block on the right. The emergency entrance is on East 9th Street.

• Yazoo City is 31 miles west of Canton on Hwy 16
• 45 miles north of Jackson on US 49
• 52 miles south of Greenwood on US 49E
• 48 miles from Vicksburg on Hwy 3/US 61
• 73 miles from Greenville on US 49E/US 82